Medicines or as people also call them drugs, can cause numerous different side-effects on and inside the human body. They particularly cause damage to the kidneys, which are a part of the group of the most important organs in our body. The list of these drugs is extremely long, but there, we’re presenting you the top 10 of them that cause the greatest damage. They include antibiotics, analgesics etc.
Top ten drugs that cause kidney damage:
- Antibiotics that include ciprofloxacin, methicillin, vancomycin, sulfonamides.
- Analgesics, including acetaminophen and non-steroidal anti-inflammatory drugs (NSAID): aspirin, ibuprofen, naproxen, and others available only by prescription.
- COX-2 inhibitors, including celecoxib (brand name Celebrex). Two drugs in this class have already been withdrawn from the market because of cardiovascular toxicity: rofecoxib (brand name Vioxx), and valdecoxib (brand name Bextra). These drugs are a special class of NSAID and were developed to be safer for the stomach, but have the same risk as other NSAIDs do for kidney damage.
- Heartburn drugs of the proton pump inhibitor class. They include omeprazole (brand name Prilosec), lansoprazole (brand name Prevacid), pantoprazole (brand name Protonix), rabeprazol (brand names Rabecid, Aciphex), esomeprazole (brand names Nexium, Esotrex).
- Antiviral drugs, including acyclovir (brand name Zovirax) used to treat herpes infections, and indinavir and tenofovir, both of them used to treat HIV.
- High blood pressure drugs, including captopril (brand name Capoten).
- Rheumatoid arthritis drugs, including infliximab (brand name Remicade); chloroquine and hydroxychloroquine, used to treat malaria and systemic lupus erythematosus as well as rheumatoid arthritis.
- Lithium, used to treat bipolar disorder.
- Anticonvulsants, including phenytoin (brand name Dilantin) and trimethadione (brand name Tridione), used to treat seizures, as well as other conditions.
- Chemotherapy drugs, including interferons, pamidronate, cisplatin, carboplatin, cyclosporine, tacrolimus, quinine, mitomycin C, bevacizumab, as well as anti-thyroid drugs, including propylthiouracil, used to treat an overactive thyroid.